Development of microglia-targeting adeno-associated viral vectors as tools to study microglial behavior in vivo

HIGHLIGHTS

  • who: Yukihiro Okada from the Gunma University have published the research: Development of microglia-targeting adeno-associated viral vectors as tools to study microglial behavior in vivo, in the Journal: (JOURNAL) of 31/Oct/2022
  • what: The authors electrophysiologically examined whether GFP-miR.T-positive PCs showed functional abnormalities compared to control PCs expressing GFP alone (without miR.T) under the control of the same promoter (upper panel Supplementary Fig 10a).
  • how: This result is consistent with a recent report55 showing that fully complementary targets (as in the present case) are cleaved when . . .

     

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