Development of novel pt(iv)-carbohydrate derivatives as targeted anticancer agents against osteosarcoma

HIGHLIGHTS

  • who: Eoin Moynihan and collaborators from the Department of Chemistry, University, F, Faenza, Italy have published the Article: Development of Novel Pt(IV)-Carbohydrate Derivatives as Targeted Anticancer Agents against Osteosarcoma, in the Journal: (JOURNAL)
  • what: The authors report the synthesis of four novel carbohydrate-modified Pt(IV) pro-drugs based on the cisplatin scaffold and their biological activity (OS) a malignant tumour which is most common in adolescents and young adults. The next step in the studies is the synthesis and characterisation of analogous complexes, where the carbohydrate is conjugated via the C2 carbon . . .

     

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