Development of novel sirna therapeutics: a review with focus on inclisiran for the treatment of hypercholesterolemia

HIGHLIGHTS

  • who: GalNAc-conjugated et al. from the Department of Chemistry, Faculty of Natural Science, Mangosuthu University of Technology, Umlazi, South Africa have published the research work: Development of Novel siRNA Therapeutics: A Review with Focus on Inclisiran for the Treatment of Hypercholesterolemia, in the Journal: (JOURNAL)
  • what: The results of this study demonstrated clinical evidence for the use of PCSK9 as a therapeutic target for a significant reduction in LDL cholesterol, which can be effective for at least six months after starting treatment. The Phase 3 trial focused on evaluating the use of inclisiran in . . .

     

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