Development of spiro-3-indolin-2-one containing compounds of antiproliferative and anti-sars-cov-2 properties

HIGHLIGHTS

• who: Nehmedo G. Fawazy from the DepartmentCardiff University have published the Article: Development of spiro-3-indolin-2-one containing compounds of antiproliferative and anti-SARS-CoV-2 properties, in the Journal: Scientific Reports Scientific Reports
• what: The targeted (E)-1″-(alkanesulfonyl)-4′-aryl-5″-arylidene-1′-methyl-dispiro[indoline-3,2′pyrrolidine-3′,3″-piperidine]-2,4″-diones 6a‒o were regioselectively synthesized through multi-component dipolar cycloaddition reaction of 1-(alkylsulfonyl)-3,5-bis(ylidene)-piperidin-4-ones 3a‒h and azomethine ylide.
• future: The comparative predicted properties due to the . . .
  

   

  

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