Development of tgfβ-il-2/15 switch receptor for use in adoptive cell therapy carole beck nicholas paul casey irene neda nejati adam yixin

HIGHLIGHTS

  • who: MDPI from the Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo have published the research: Development of TGFu03b2-IL-2/15 Switch Receptor for Use in Adoptive Cell Therapy Carole Beck Nicholas Paul Casey Irene Neda Nejati Adam Yixin, in the Journal: Biomedicines 2023, 11, 459. of /2023/
  • what: The study showed acceptable safety and a PSA30 response in 4 of 10 patients . The aim of this study was to develop a construct conferring tumor-targeting T_cells with improved functionality in a TGFu03b2-rich environment.
  • how: The results . . .

     

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