Development of therapeutic antibodies for the treatment of diseases

HIGHLIGHTS

  • who: Zeng Wang from the Regulatory review in China have published the article: Development of therapeutic antibodies for the treatment of diseases, in the Journal: (JOURNAL) of July/19,/2022
  • what: The authors focus on several key technologies for the early preparation and screening of antibody drugs, including hybridoma technology, phage display human antibody libraries, human antibodies from transgenic mice, single B-cell antibody technology, and AI-assisted antibody discovery. For instance, using AlphaFold begins with the sequences and structures of approximately 100,000 known proteins to train the model, and then results in a . . .

     

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