HIGHLIGHTS
- who: CNTNAP and collaborators from the University Hospital Essen, Germany have published the Article: Developmental de cits of MGE-derived interneurons in the knockout mouse model of autism spectrum disorder, in the Journal: (JOURNAL)
- what: The authors show that interneuron production, migration and integration in the developing striatum are affected in the Cntnap2 KO mouse model, likely contributing to ASD-related pathogenesis. By uncovering preferential and specific developmental modifications of the striatal interneuron maturation at embryonic and early postnatal stages, the authors demonstrate that the MGE-derived Lhx6+ CINs, which represent at least 50% of . . .
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