HIGHLIGHTS
- who: Sebastien G. Bouret from the (UNIVERSITY) have published the research: Developmental programming of hypothalamic melanocortin circuits, in the Journal: (JOURNAL)
- what: It is now clear from a variety of epidemiological and experimental studies that many chronic diseases, including obesity and type-2 diabetes, may have their roots during neonatal development.
- future: Studies are needed to determine the developmental stage during which MC4R becomes functional. Otp expression is absent in the hypothalamus of Isl1 knockout embryos58 suggesting that in addition to Dlx1/2 Isl1 is also required for the expression of Otp in . . .
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