HIGHLIGHTS
- who: Sara Gurule and colleagues from the Instituto Estadual do Cu00e9rebro Paulo Niemeyer (IECPN), Brazil Fudan University, China have published the article: Developmental programming of the neuroendocrine axis by steroid hormones: Insights from the sheep model of PCOS, in the Journal: (JOURNAL)
SUMMARY
On the flip side, elevated concentrations of androgens impair the responsiveness of the neuroendocrine system to the progesterone and estradiol negative_feedback mechanisms on tonic secretion of GnRH and LH, thus creating a vicious circle between LH hypersecretion and hyperandrogenism. The effects of prenatal testosterone treatment reducing the responsiveness to the . . .
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