Developmental transcriptional networks are required to maintain neuronal subtype identity in the mature nervous system

HIGHLIGHTS

• who: Kevin T. Eade and colleagues from the Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada have published the research work: Developmental Transcriptional Networks Are Required to Maintain Neuronal Subtype Identity in the Mature Nervous System, in the Journal: (JOURNAL) of February/23,/2012
• what: The authors show that certain critical cross-regulatory relationships that had existed between these transcription factors during development were no longer present in the mature adult neuron. The authors show that the TF networks that establish unique gene_expression profiles during development are then required to maintain . . .
  

   

  

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