Diacylglycerol and its formation by phospholipase c regulate rab- and snare-dependent yeast vacuole fusion*

HIGHLIGHTS

• who: Youngsoo Jun from the Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire, promoter (a generous gift from DrJeremy Thorner, University of have published the article: Diacylglycerol and Its Formation by Phospholipase C Regulate Rab- and SNARE-dependent Yeast Vacuole Fusion*, in the Journal: (JOURNAL)
• what: Vacuole was blocked 3-nitrocoumarin at comparable concentration (Ki ⬍ whereas its inactive analogue 7-hydroxy-3-nitrocoumarin had little effect vacuole (Fig 2A). has been used an inhibitor for mammalian PLCs and plant PLCs . prevented vacuole with Ki of whereas its structural analogue did inhibit (Fig 2B). also . . .
  

   

  

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