HIGHLIGHTS
- who: Federico Comitani from the (UNIVERSITY) have published the paper: Diagnostic classification of childhood cancer using multiscale transcriptomics, in the Journal: (JOURNAL) of 21/03/2022
- what: The authors show that this tool was able to match or clarify the diagnosis for 85% of childhood tumors in a prospective cohort.
- how: The authors used an optimized multilevel RNA clustering approach to derive molecular definitions for most childhood cancers.
SUMMARY
As a whole, childhood tumors had more transcriptional diversity than adult tumors, maintaining greater expression flexibility. Compared to adult cancers . . .
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