Diagnostic gene signatures and aberrant pathway activation based on m6a methylation regulators in rheumatoid arthritis

HIGHLIGHTS

• who: Qishun Geng and collaborators from the Anhui Medical University, China have published the Article: Diagnostic gene signatures and aberrant pathway activation based on m6A methylation regulators in rheumatoid arthritis, in the Journal: (JOURNAL)
• what: Considering the poorest performance of the Rpart model, the authors focused on the overlapping m6A methylation regulators selected by the different machine_learning methods, including of random forest optimization using Boruta, LASSO, XGBoost and logistic regression . Cell types, the authors focused on M1 macrophages because of the closely relationship between M1 macrophages and RA . The primary aim in this study was . . .
  

   

  

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