Dibenzoylthiamine has powerful antioxidant and anti-inflammatory properties in cultured cells and in mouse models of stress and neurodegeneration

HIGHLIGHTS

  • who: Bernard Coumans and collaborators from the Laboratory of Neurophysiology, GIGA-Neurosciences, University of Liège, Liège, BelgiumFaculty of Sciences, University of Girona, Girona, Spain have published the article: Dibenzoylthiamine Has Powerful Antioxidant and Anti-Inflammatory Properties in Cultured Cells and in Mouse Models of Stress and Neurodegeneration, in the Journal: Biomedicines 2020, 8, x FOR PEER REVIEW of /2020/
  • what: The authors show that DBT protects Neuro2a cells against paraquat (PQ) toxicity by counteracting oxidative stress at low concentrations and increases the synthesis of reduced glutathione and NADPH in a Nrf2-independent manner . . .

     

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