HIGHLIGHTS
SUMMARY
The loss of DKK3 gene_expression in cancer is frequently a consequence of gene promoter methylation, which varies between 14% in non-small cell lung cancer and 78% in breast cancer. Dkk-3 has been reported to be involved in the differentiation of induced pluripotent and embryonic stem_cells. The expression of Dkk-3 in mesenchymal stem_cells also limits CD8+ and CD4+ T_cell-mediated responses to suppress the process of inflammation. Mesenchymal stem_cells are known to suppress the growth of tumors by inhibiting T_cell proliferation, the induction of T regulatory cells, and facilitating the generation of . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.