HIGHLIGHTS
- who: Tomoki Uchikawa from the DepartmentKyushu University, Fukuoka, Japan have published the Article: Dietary 7-ketocholesterol exacerbates myocardial ischemia-reperfusion injury in mice through monocyte/macrophage-mediated inflammation, in the Journal: Scientific Reports Scientific Reports
- what: This study investigated the effects of exogenous 7-KC in a mouse myocardial IR injury model and in cultured monocytes/macrophages. The authors reported the adverse effect of dietary 7-KC in the WT murine IR model for the first time. The authors employed unbiased transcriptomic analysis and determined the molecular mechanisms of 7-KC-induced inflammation in monocytes . . .
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