HIGHLIGHTS
SUMMARY
It has been generally reported that the intake of dietary sources rich in_(poly)phenols and/or fiber can shape the GM by promoting the abundance of beneficial bacteria and inhibiting some pathogenic microbial groups whereas food chemicals can disrupt human GM and impact negatively the intestinal homeostasis. Studies focusing on the association between xenobiotics and GM are still scarce and data available are mainly from in_vitro models and in_vivo murine models. In this regard, Kim and Hur found during in_vitro simulated human digestion, that the mutagenicity of HAs was drastically reduced in the . . .
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