HIGHLIGHTS
SUMMARY
The Omicron variant, in fact, turned out to be characterized by a higher transmission rate and several mutations in the spike_protein leading to a reduction in the protection afforded by both vaccine-induced and natural_immunity (a growing trend for the relative risk of reinfection from 6 December 2021 was revealed ). For all these reasons, the work has been designed to evaluate the effectiveness of both natural_immunity and the three-dose regimen against Delta and Omicron infections. As stated previously, to avoid misclassification for "reinfection" and considering the protection afforded by multiple preceding infections, the . . .
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