Differences in mutational processes and intra-tumour heterogeneity between organs

HIGHLIGHTS

• who: The local selective filter and colleagues from the University of Tartu, Vanemuise, Tartu, EstoniaToulouse, France have published the research: Differences in mutational processes and intra-tumour heterogeneity between organs, in the Journal: (JOURNAL) of 12/Nov/2018
• what: The authors provide a comprehensive overview of this hypothesis. The authors propose that mostly aggressive neoplasms (i.e. higher mutational and ITH levels), succeed in emerging and developing in organs with strong defences. The authors propose that variation in mutational patterns and ITH result from the evolutionary ecology of organs' theory , and are therefore explained by . . .
  

   

  

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