Differential epithelial and stromal lgr5 expression in ovarian carcinogenesis

HIGHLIGHTS

  • who: Hyesung Kim from the DepartmentNational University have published the research work: Differential epithelial and stromal LGR5 expression in ovarian carcinogenesis, in the Journal: Scientific Reports Scientific Reports
  • what: The authors thoroughly investigated LGR5 expression in human ovaries and fallopian tubes as well as related benign and malignant ovarian tumors.
  • how: The authors examined whether Wnt signaling activity is responsible for the high levels of LGR5 expression observed in ovarian carcinomas by examining the correlation between nuclear u03b2-catenin and LGR5 expression.

SUMMARY

    The authors examined whether Wnt signaling . . .

     

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