Differential ganglioside and cholesterol depletion by various cyclodextrin derivatives and their effect on synaptosomal glutamate release

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  • who: Orsolya Geda and colleagues from the Department of Pharmacodynamics, Semmelweis University, Nagyvárad tér, Budapest, Hungary have published the research work: Differential Ganglioside and Cholesterol Depletion by Various Cyclodextrin Derivatives and Their Effect on Synaptosomal Glutamate Release, in the Journal: (JOURNAL)
  • what: The aim of this research was to investigate the effect of dimethyl-beta-cyclodextrin (DIMEB) hydroxypropyl-beta-cyclodextrin (HPBCD) randomly methylated-alpha-cyclodextrin (RAMEA) and hydroxypropyl-alpha-cyclodextrin (HPACD) on ganglioside and cholesterol levels in rat brain synaptosomes. As CD treatments induced considerable changes in the membrane lipid composition, the authors . . .

     

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