Differential grey matter structure in women with premenstrual dysphoric disorder: evidence from brain morphometry and data-driven classification

HIGHLIGHTS

• who: Manon Dubol from the Smaller grey matter volumes (GMV) and thinner cortices have been observed in relation to several mental disorders sharing aspects of PMDD symptomatology, including anxiety disorders and major depression [11-14]Further, individuals with major depression and anxiety disorders respectively display lower and greater gyrification of the cortex in comparison with healthy controls [12, ]. On top of the disorder-specific brain structural alterations, there is increasing evidence that periods involving profound changes in ovarian hormone levels, like puberty, pregnancy and even the menstrual cycle, are associated with brain morphometric changes in women [7 . . .
  

   

  

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