Differential methylation of microrna encoding genes may contribute to high myopia

HIGHLIGHTS

  • who: . and colleagues from the Cardiff University, United Kingdom have published the paper: Differential methylation of microRNA encoding genes may contribute to high myopia, in the Journal: (JOURNAL)
  • what: The authors report significant increase in methylation level of CG dinucleotides located in the promoter regions of MIR3621, MIR34C, MIR423, and significant decrease in the promoter regions of MIR1178, MIRLET7A2, MIR885, MIR548I3, MIR6854, MIR675, MIRLET7C, and MIR99A genes. To compliment the already performed analyses on differentially methylated genes in HM in Polish children (Vishweswaraiah et_al, 2019; Swierkowska et_al, 2022), the authors focused here on CG dinucleotides . . .

     

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