Differential progression of unhealthy diet-induced hepatocellular carcinoma in obese and non-obese mice

HIGHLIGHTS

  • who: Emma Hymel et al. from the Department of Epidemiology, College of Public Health, University of Nebraska Medical Center, Omaha have published the research work: Differential progression of unhealthy diet-induced hepatocellular carcinoma in obese and non-obese mice, in the Journal: PLOS ONE of October/14,/2021
  • what: The authors generated a mouse model of lean and obese NASH-HCC using a choline deficient/high trans-fat/fructose/cholesterol diet and a choline supplemented/high trans-fat/ fructose/cholesterol diet, respectively, to compare progression to NASH-HCC in lean versus obese mice.
 

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