Differential proteomic analysis of astrocytes and astrocytes-derived extracellular vesicles from control and rai knockout mice: insights into the mechanisms of neuroprotection

HIGHLIGHTS

• who: Tommaso Montecchi et al. from the Department of Life Sciences, University of Siena, Via Aldo Moro, , Siena, Italy have published the research work: Differential Proteomic Analysis of Astrocytes and Astrocytes-Derived Extracellular Vesicles from Control and Rai Knockout Mice: Insights into the Mechanisms of Neuroprotection, in the Journal: (JOURNAL)
• what: The authors show that the IL-17-dependent expression of HIF-1↵ is inhibited in Rai / astrocytes.
• how: Using primary mouse astrocytes the authors showed that Rai contributes to the generation of a pro-inflammatory central nervous system (CNS) microenvironment through the . . .
  

   

  

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