Differential regulation of h3k9/h3k14 acetylation by small molecules drives neuron-fate-induction of glioma cell

HIGHLIGHTS

  • who: Xincheng Liu from the , Subcutaneous and intracranial xenograft GBM models Animal studies were approved by the Animal Ethical and Welfare Committee of Sun Yat-sen UniversityThe hind flanks of, week-old female BALB/c-nu/nu mice were subcutaneously inoculated with , u00d7 , cells. The mice were randomly divided into , groups after tumor cell injection and were injected intraperitoneally once per day with vehicle, mg/kg dbcAMP (Sigma-Aldrich, USA), mg/kg luteolin (Selleck, USA), mg/kg , (Selleck), mg/kg temozolomide (Topscience, USA) or a combination of these drugs. Tumor diameters were measured every other day with . . .

     

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