HIGHLIGHTS
- who: CNS and colleagues from the Departments of Environmental Health and Pharmacology, University of Washington, Seattle, Washington, have published the paper: Differential Regulation of Mitogen-Activated Protein Kinases ERK1/2 and ERK5 by Neurotrophins, Neuronal Activity, and cAMP in Neurons, in the Journal: (JOURNAL) of January/15,/2001
- what: The authors examined the regulation of ERK5 signaling in primary cultures of cortical neurons and in PC12 cells. The authors report that ERK5 is activated by neurotrophins but not by neuronal activity or cAMP in cortical neurons. In contrast, both glutamate and membrane depolarization induced ERK1 . . .
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