HIGHLIGHTS
- who: Bingnan Li from the (UNIVERSITY) have published the paper: Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation, in the Journal: (JOURNAL)
- what: The work shows that gene-specific differences in intrinsic nuclear surveillance factor association can enhance both gene induction and repression in primed cells. The authors show that primed cells present altered levels of RNA degradation machinery and that both nuclear and cytoplasmic mRNA decay modulate transcriptional memory. The authors focused on the role of nuclear mRNA surveillance, since two components of the nuclear exosome (RRP6 and LRP1) were . . .
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