Differential regulation of sterol regulatory element-binding protein 1c transcriptional activity by insulin and liver x receptor during liver development*

HIGHLIGHTS

  • who: Alexandre Bobard from the (UNIVERSITY) have published the paper: Differential Regulation of Sterol Regulatory Element-binding Protein 1c Transcriptional Activity by Insulin and Liver X Receptor during Liver Development*, in the Journal: (JOURNAL) of June/11,/2004
  • what: The aim of this study was to investigate the regulation of the hepatic SREBP-1c expression in_vivo in situations where drastic nutritional and hormonal changes occur, from the gestation to the weaning period. The authors report the discovery of LXR-independent SREBP-1c transcriptional activity during late gestation. The authors propose that LXR, a known activator . . .

     

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