Differential regulation of two arms of mtorc1 pathway fine-tunes global protein synthesis in resting b lymphocytes

HIGHLIGHTS

  • who: Gagan Dev and collaborators from the National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi, Delhi, India MRC Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee have published the article: Differential Regulation of Two Arms of mTORC1 Pathway Fine-Tunes Global Protein Synthesis in Resting B Lymphocytes, in the Journal: (JOURNAL)
  • what: The authors show that resting B cells despite being quiescent exhibit increased synthesis in vivo as well as ex vivo. The observation made in this study shows that mRNAs coding for MHC Class II and their chaperone CD74 . . .

     

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