Differential repair protein recruitment at sites of clustered and isolated dna double-strand breaks produced by high-energy heavy ions

HIGHLIGHTS

• who: Burkhard Jakob from the Department of Biophysics, GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt, Germany have published the article: Differential Repair Protein Recruitment at Sites of Clustered and Isolated DNA Double-Strand Breaks Produced by High-Energy Heavy Ions, in the Journal: Scientific Reports Scientific Reports
• what: The study shows that DDR kinetics is strongly influenced by damage complexity. While additional factors like the local chromatin environment (e_g heterochromatin44) can contribute to differences as well, the authors propose that enzymatic processing and conversion of non-DSB lesions play major roles in the repair kinetics of . . .
  

   

  

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