Differential sensitivity of human islets from obese versus lean donors to chronic high glucose or palmitate

HIGHLIGHTS

• who: Françoise Castex et al. from the have published the article: Differential sensitivity of human islets from obese versus lean donors to chronic high glucose or palmitate, in the Journal: (JOURNAL)
• what: Obesity is known to be associated with a modest expansion of β-cell mass, reaching 10% to 30% per 10 kg weight gain so the authors cannot exclude an increase in β-cell mass; however, in the study , the authors did not observe a significant change in islet size of obese subjects compared to lean ones. The authors propose that decreased nitrosative stress induced . . .
  

   

  

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