Differentiation of human adult-derived stem cells towards a neural lineage involves a dedifferentiation event prior to differentiation to neural phenotypes

HIGHLIGHTS

  • who: Carlos Bueno from the InstitutUniversity of have published the research: Differentiation of human adult-derived stem cells towards a neural lineage involves a dedifferentiation event prior to differentiation to neural phenotypes, in the Journal: Scientific Reports Scientific Reports of 27/05/2021
  • what: The authors have shown that hPDLSCs, hBMSCs and hDPSCs can directly differentiate into neuron-like cells without passing through a mitotic stage.

SUMMARY

    Time-lapse imaging revealed that the hPDLSC-derived neuron-like cells connected to one another through different types of interactions (Fig 2c, red arrows . . .

     

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