HIGHLIGHTS
- who: DNA et al. from the Central South University, China have published the research: Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage, in the Journal: (JOURNAL)
- what: The fact that this work has not explored the in_vivo efficacy of DHA was a limitation. This work shows that DHA-triggered ferroptosis of TAM results in DNA damage, which could activate downstream NF-κB to remodel TAM to the M1 phenotype , providing a novel strategy for anti-lung cancer immunotherapy.
- how: RT-PCR was performed using a Bio-RAD CFX Connect . . .
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