HIGHLIGHTS
- who: Corrected Author Correction et al. from the Université University of have published the research work: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor, in the Journal: Scientific Reports Scientific Reports
- what: The aim of this study was to better understand the role of this nuclear receptor in the sex-dependent regulation of energy homeostasis and in the development of metabolic diseases. The authors show that CAR-/- male mice develop significant metabolic disorders, including obesity, diabetes, and liver steatosis. Using a mouse model invalidated for the CAR nuclear receptor that the . . .
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