Direct activation of a bacterial innate immune system by a viral capsid protein

HIGHLIGHTS

• who: Tong Zhang from the (UNIVERSITY) have published the research: Direct activation of a bacterial innate immune system by a viral capsid protein, in the Journal: (JOURNAL) of 26/05/2022
• what: Using genetic, biochemical and structural analyses, the authors demonstrate that the C-terminal domain of CapRelSJ46 regulates the toxic N-terminal region, serving as both antitoxin and phage infection sensor. The authors provide evidence that CapRels and their phage-encoded triggers are engaged in a u2018Red Queen conflict`5, revealing a new front in the intense coevolutionary battle between phages and bacteria. Next . . .
  

   

  

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