Direct cytosolic delivery of citraconylated proteins

HIGHLIGHTS

  • who: Ritabrita Goswami and collaborators from the Department of Chemistry, University of Massachusetts Amherst, North Pleasant Street, Amherst, MA, USA have published the paper: Direct Cytosolic Delivery of Citraconylated Proteins, in the Journal: Pharmaceutics 2023, x of /2023/
  • what: The authors report the use of a straightforward approach of protein modification using citraconic anhydride to impart an overall negative charge on the proteins enabling them to assemble with positively charged nano vectors.
  • how: Imaging flow cytometry For flow imaging the authors used an Amnis ImageStream MkII Imaging Flow Cytometer (Luminex Austin TS USA . . .

     

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