Direct evidence for substrate-induced proton release in detergent-solubilized emre, a multidrug transporter*

HIGHLIGHTS

• who: Misha Soskine from the (UNIVERSITY) have published the paper: Direct Evidence for Substrate-induced Proton Release in Detergent-solubilized EmrE, a Multidrug Transporter*, in the Journal: (JOURNAL) of November/25,/2003
• what: The authors show, for the first time in an ion-coupled transporter, substrate-induced release of protons in a detergent-solubilized preparation. The pH Dependence of H⫹ Release Allows Estimation of pK of Glu-14 -The studies described above were performed at pH 7.0, where the response to substrate was maximal. The authors propose that the decrease is due to a . . .
  

   

  

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