Direct injection of functional single-domain antibodies from e. coli into human cells

HIGHLIGHTS

• who: Ana Blanco-Toribio and colleagues from the Department of Microbial Biotechnology, Centro Nacional de Biotecnologı́a, Consejo Superior de Investigaciones Cientı́ficas (CSIC), Campus Cantoblanco Universidad College London, London, United Kingdom have published the article: Direct Injection of Functional Single-Domain Antibodies from E. coli into Human Cells, in the Journal: (JOURNAL)
• what: The authors demonstrate that single-domain Ab (sdAbs) can be engineered to be injected into human cells by E. coli bacteria carrying molecular syringes assembled by a type III protein secretion system (T3SS). The authors have shown that noninvasive E. coli . . .
  

   

  

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