Direct interaction between n-acetylcysteine and cytotoxic electrophile—an overlooked in vitro mechanism of protection

HIGHLIGHTS

  • who: Petr Mlejnek from the Department of Anatomy, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hnevotinska , have published the Article: Direct Interaction between N-Acetylcysteine and Cytotoxic Electrophileu2014An Overlooked In Vitro Mechanism of Protection, in the Journal: Antioxidants 2022, 11, 1485. of /2022/
  • what: A number of cytotoxic agents that are electrophiles induce cell death that is accompanied by ROS production and/or GSH depletion, and all the adverse effects can be prevented by millimolar concentrations of NAC.

SUMMARY

    In laboratory experiments, NAC is the most commonly used protective agent . . .

     

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