Direct measurements of mrna translation kinetics in living cells

HIGHLIGHTS

  • who: Mikhail Metelev from the Uppsala University have published the paper: Direct measurements of mRNA translation kinetics in living cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: Initial applications of this approach have mostly been limited to the identification of cellular localizations of molecules in different functional states, whereas the dynamics of the processes has been out of reach due to limited photostability of the fluorescent proteins which have dominated the field of live-cell fluorescence microscopy. The authors demonstrate that the authors can readily detect subtle changes in translation initiation kinetics as a . . .

     

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