Direct observation of compartment-specific localization and dynamics of voltage-gated sodium channels

HIGHLIGHTS

  • who: Significance Statement and collaborators from the Institute, New York, New York , have published the research: Direct Observation of Compartment-Specific Localization and Dynamics of Voltage-Gated Sodium Channels, in the Journal: (JOURNAL) of July/13,/2022
  • what: The authors reason that the small size of these tags would minimize the risk of perturbing their physiological functions. Because of conserved sequence homology in membrane embedded domains, the authors focused on intracellular loops, J. Neurosci .
  • how: For tracking JF549-labeled single molecules the authors used a 561 nm laser with the excitation power of . . .

     

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