Direct transcriptomic comparison of xenobiotic metabolism and toxicity pathway induction of airway epithelium models at an air-liquid interface generated from induced pluripotent stem cells and primary bronchial epithelial cells

HIGHLIGHTS

  • who: Ivo Djidrovski from the Harwell Campus, Chilton , RQ, UKCentre for Life, Newcastle University, Central have published the article: Direct transcriptomic comparison of xenobiotic metabolism and toxicity pathway induction of airway epithelium models at an air-liquid interface generated from induced pluripotent stem cells and primary bronchial epithelial cells, in the Journal: (JOURNAL)
  • what: The authors report a comparative analysis by TempoSeq (oligo-directed sequencing) of an iPSC-derived model (iBAE) with a primary bronchial model (pBAE). The study shows that iPSC models for the modelling of lung airways at ALI may be a useful . . .

     

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