HIGHLIGHTS
- who: Seong Guk Park from the Department of Biological Sciences, National Institute of Science Department of Medicine, Graduate School, University, Seoul have published the article: Directing ricin-based immunotoxins with targeting affibodies and KDEL signal peptide to cancer cells effectively induces apoptosis and tumor suppression, in the Journal: (JOURNAL)
- what: The authors constructed ricin-based RITs comprising the RTA, affibody molecules, and the KDEL signal peptide, and evaluated their target-specific cytotoxicity against corresponding target cancer cells. Based on the results , the authors propose a working model for intracellular delivery of ricin-based RITs constructed . . .
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