Disaccharide-tag for highly sensitive identification of o-glcnac-modified proteins in mammalian cells

HIGHLIGHTS

  • who: Hirohito Abo and collaborators from the Faculty of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan have published the research work: Disaccharide-tag for highly sensitive identification of O-GlcNAc-modified proteins in mammalian cells, in the Journal: PLOS ONE of April/14,/2022
  • what: Proteins, the authors focused on the transcription factor Sox2 because this protein was reported to be involved in the selfrenewal of ESCs, and its O-GlcNAcylation was also discussed .
  • how: Experiments using human materials and genetic_recombination experiments were conducted in accordance with . . .

     

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