Discovery and characterization of heterogeneous and multipotent fibroblast populations isolated from excised cleft lip tissue

HIGHLIGHTS

  • who: Ludovica Parisi from the Laboratory for Oral Molecular Biology, Department of Orthodontics and Dentofacial Orthopedics, University of Bern, Bern, Switzerland have published the paper: Discovery and characterization of heterogeneous and multipotent fibroblast populations isolated from excised cleft lip tissue, in the Journal: (JOURNAL)
  • what: Using IF and immunoblots, the authors demonstrate that FN is synthesized (intracellular staining and total cell extracts), secreted (CM), and deposited (staining of extracellular decellularized matrix) by CLP1-CLP5. Next, the authors aimed to comparatively assess the induction of several lineagespecific differentiation markers in CLP1-CLP3 and BMMSCs (Fig 2d . . .

     

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