Discovery and optimization of selective inhibitors of meprin (part i)

HIGHLIGHTS

  • who: Shurong Hou and collaborators from the Department of Molecular Medicine, The Scripps Research Molecular Screening Center, Scripps Research, Rumbaugh-Goodwin Institute for Cancer Research, Nova Southeastern University, College Fort Lauderdale, FL, USA have published the Article: Discovery and Optimization of Selective Inhibitors of Meprin (Part I), in the Journal: Pharmaceuticals 2021, 14, x FOR PEER REVIEW of /2021/
  • how: The counter screens were conducted in triplicate using the same 2378 compounds that were tested in confirmation assays. Cheminformatics analysis of the Scripps HTS assay database containing hundreds of biological assay results showed that 660 . . .

     

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