Discovery and synthesis of hydroxy-l-proline blockers of the neutral amino acid transporters slc1a4 (asct1) and slc1a5 (asct2)

HIGHLIGHTS

• What: The authors demonstrate the beginnings of a structure-activity relationship (SAR) investigation of hydroxyprolines as inhibitors of the neutral amino_acid transporters SLC1A4 and SLC1A5.
• Who: Brent R. Lyda and collaborators from the Division of Biological Sciences, University of Montana, Campus Dr, Missoula, MT, USA have published the research: Discovery and Synthesis of Hydroxy-l-Proline Blockers of the Neutral Amino Acid Transporters SLC1A4 (ASCT1) and SLC1A5 (ASCT2), in the Journal: Molecules 2024, 29, x FOR PEER REVIEW of 15/05/2024

SUMMARY

SLCs encompass over 400 members across 65 distinct . . .

 



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