Discovery of β-arrestin-biased 25cn-nboh-derived 5-ht2a receptor agonists

HIGHLIGHTS

• who: Christian B. M. Poulie and colleagues from the (UNIVERSITY) have published the article: Discovery of u03b2-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists, in the Journal: (JOURNAL) of September/13,/2022
• what: The authors have evaluated the subtype-selective 5-HT2AR agonist 25CN-NBOH and a series of close analogues for biased signaling at receptor. In recent years there has been increased scientific interest in these serotonergic psychedelics primarily based on the work with psilocybin which has displayed promising effects in clinical studies focused on various neuropsychiatric indications including depression and anxiety . . .
  

   

  

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