HIGHLIGHTS
- who: Rui Min and colleagues from the Graduate School at Shenzhen, Tsinghua University, Shenzhen, China have published the article: Discovery of 2-(1-(3-(4-Chloroxyphenyl)-3-oxo- propyl)pyrrolidine-3-yl)-1H-benzo[d]imidazole-4- carboxamide: A Potent Poly(ADP-ribose) Polymerase (PARP) Inhibitor for Treatment of Cancer, in the Journal: (JOURNAL)
- what: A series of benzimidazole carboxamide derivatives have been synthesized and their PARP inhibition activities and cellular activities have been detected.
- how: The molecular docking experiment was implemented in four steps
SUMMARY
Besides competitively inhibiting . . .
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